Figure 4

Effects of Cur-AgNPs on wound healing induction. (a) Human dermal fibroblast cells were treated with 0.03 and 0.06 nM of Cur-AgNP, or 100 ng/mL of rhFGF-b as a positive control, and a scratch wound assay performed at 0, 24 and 48 h after scratch wounding (compared to no treatment as a negative control). (b) Analyzed percentage wound gap width after 48 h relative to the original scratch width. Data were expressed as mean ± SEM (n = 3). *P < 0.05 and ***P < 0.001 compared to control within 24 h post-treatment. ^†P < 0.005 and ^†††P < 0.001 compared to negative control within 48 h post-treatment.