Table 7 Binding free energy (ΔG) of the compounds.
From: New chalcone derivatives as potential antimicrobial and antioxidant agent
Gram-positive bacteria | Gram-negative bacteria | Fungi | ||||
|---|---|---|---|---|---|---|
B. subtilis (2V F5) | S.aureus (3G75) | P.aeruginosa (3P3E) | E.coli (1GRX) | C.albicans (1AI9) | A.niger (1WS3) | |
Compound | ||||||
6a | − 10.29 | − 10.86 | − 10.49 | − 9.20 | − 10.91 | − 9.46 |
6b | − 9.32 | − 9.40 | − 9.49 | − 8.07 | − 10.17 | − 9.44 |
6c | − 10.69 | − 10.55 | − 11.45 | − 8.99 | − 11.70 | − 9.58 |
6d | − 9.20 | − 10.81 | − 10.48 | − 8.79 | − 11.68 | − 9.60 |
6e | − 11.54 | − 11.32 | − 13.09 | − 10.15 | − 11.47 | − 10.95 |
6f | − 8.97 | − 9.81 | − 9.61 | − 8.46 | − 11.00 | − 9.07 |
6g | − 12.53 | − 11.99 | − 12.54 | − 10.85 | − 12.39 | − 10.77 |
Std drug | − 12.93 | − 12.12 | − 13.22 | − 11.20 | − 10.70 | − 9.40 |
Native ligand | − 13.61 | − 10.29 | − 11.68 | − 12.81 | − 19.04 | − 7.03 |
