Table 1 Baseline characteristics of the NDMM patients.
Characteristics | n = 64 |
|---|---|
Gender (male) | 41 (64.1%) |
Median age (years) | 60 (36–85) |
M protein type | |
IgG | 28 (43.7%) |
IgA | 18 (28.1%) |
LC | 13 (20.3%) |
IgD | 5 (7.9%) |
Hemoglobin (g/L) | 97.5 (42–182) |
M protein in SPE (g/L)* | 35.6 (0–99.8) |
24-h urine LC (mg)** | 8252 (275–56,000) |
BM myeloma cells (%) | 26% (0–88%) |
LDH > 250 U/L | 12 (18.7%) |
Serum β2-MG (mg/L) | 6.08 (0.6–67.4) |
ISS staging | |
I | 9 (14.1%) |
II | 20 (31.3%) |
III | 35 (54.7%) |
D–S staging | |
IA | 4 (6.3%) |
IB | 2 (3.1%) |
IIA | 6 (9.4%) |
IIIA | 38 (59.4%) |
IIIB | 14 (21.9%) |
CA by FISH | |
1q21+ | 24 (37.5%) |
RB1− | 28 (43.8) |
DS319− | 28 (43.8%) |
17p− | 11 (17.2%) |
t (14;16) | 3 (4.9%) |
t (4;14) | 7 (10.9%) |
t (11;14) | 8 (12.5%) |
High risk disease | 30 (46.9%) |