Table 2 Baseline echocardiographic parameters.

From: Combined effects of ARNI and SGLT2 inhibitors in diabetic patients with heart failure with reduced ejection fraction

 

ARNI + SGLT2i

(Group 1, N = 51)

ARNI only

(Group 2, N = 52)

SGLT2i only

(Group 3, N = 52)

Control

(Group 4, N = 51)

P value

LV-EDD (mm)

60.2 ± 6.7

60.0 ± 7.0

56.9 ± 8.4

60.7 ± 8.9

0.209

LV-ESD (mm)

50.5 ± 8.8

50.1 ± 8.2

47.3 ± 9.8

50.6 ± 10.0

0.444

LV-EDV (mL)

151.0 ± 59.9

153.5 ± 56.7

130.9 ± 48.4

158.3 ± 59.6

0.238

LV-ESV (mL)

109.4 ± 46.2

112.5 ± 51.1

91.2 ± 41.2

116.5 ± 51.9

0.189

LV-EF (%)

29.4 ± 9.5

28.3 ± 6.4

32.6 ± 10.6

27.7 ± 8.0

0.107

LV mass index (g/m2)

142.7 ± 34.4

137.2 ± 35.9

123.4 ± 19.1

159.5 ± 56.2

0.003

LA volume index (mL/m2)

60.3 ± 24.5

47.6 ± 26.7

60.3 ± 20.1

50.7 ± 18.4

0.018

Mitral annular e′ velocity (cm/s)

4.7 ± 1.7

4.5 ± 2.0

5.0 ± 2.4

4.6 ± 2.0

0.714

Mitral annular s′ velocity (cm/s)

4.7 ± 3.1

4.4 ± 1.1

4.8 ± 1.3

4.9 ± 1.9

0.734

Mitral annular E/e′ ratio

21.9 ± 14.0

22.0 ± 14.8

21.0 ± 11.4

21.6 ± 13.0

0.978

PASP (mmHg)

43.5 ± 14.4

39.3 ± 17.7

42.0 ± 14.6

37.8 ± 15.1

0.397

Global longitudinal strain (%)

7.5 ± 2.2

7.5 ± 2.4

7.6 ± 2.6

6.8 ± 2.5

0.264

  1. LV left ventricle, EDD end diastolic dimension, ESD end systolic dimension, EDV end diastolic volume, ESV end systolic volume, EF ejection fraction, PASP pulmonary artery systolic pressure. The absolute value |x| of strain is used.
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