Figure 5

Taxonomic relative abundance notably differs between cases and controls. The relative abundance of bacterial genera and phyla in each sample are displayed as columns for cases (A, C) and controls (B, D). Similar to ARG relative abundance, taxonomic relative abundances were determined using raw abundances that had been normalized by the approximate number of genome equivalents in the sample as determined using MicrobeCensus. For the phylum and genus levels, the top-10 phyla and genera were chosen, respectively, based on the highest average relative abundance assigned to a specific phylum or genus among cases or controls (which were considered separately). The remaining read abundances for phyla or genera in samples were summed and are shown in the category “Other.” Note: plots for cases (A, C) and controls (B, D) contain the same respective color schemes but that these refer to genera (A, B) and phyla (C, D), respectively.