Figure 9

Beta diversity analyses do not reveal clear similarities among 16 separate families as seen in a Principal coordinates analysis (PCoA) plot generated using Bray–Curtis dissimilarity of all samples. Case samples are depicted as circles and controls as triangles; members of the same family are represented by the same color. Environmental factors with potential to influence this ordination were also examined. The variable exploring the number of days since exposure to the case was significantly correlated with the observed ordination. These data were fitted to the ordination using the ‘envfit’ function in R and displayed with a labeled arrow in the plot. The number of days since exposure to an ill family member is correlated to more “normal” looking controls (i.e., controls that are most dissimilar from their corresponding infected cases).