Figure 1 | Scientific Reports

Figure 1

From: Effect of N-methyl-d-aspartate receptor enhancing agents on cognition in dementia: an exploratory systematic review and meta-analysis of randomized controlled trials

Figure 1

PRISMA flow diagram of the search and identification of included studies. Database: PubMed (n = 304), Cochrane Central Register of Controlled Trials (n = 208), Cochrane Database of Systematic Reviews (n = 7). Keyword: (Dementia OR Alzheimer*) AND (acetylcysteine OR α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid OR AMPA OR benzoate OR CX516 OR D-cycloserine OR D-serine OR glutamine OR glutamate OR glutamate carboxypeptidase 2 OR GCP2 OR glycine OR glycine transporter type 1 OR GlyT1 OR glutamate receptor ionotropic kainate OR GRIK OR kynurenine aminotransferase OR KAT OR metabotropic glutamate receptor OR mGluR OR minocycline OR N-acetyl-aspartylglutamate OR NAAG OR N-methyl-d-aspartate OR NMDA OR pregnenolone OR sarcosine) AND controlled trial. Date: date available to August 7th, 2020.

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