Figure 6

Light photomicrographs of the rats kidney sections (H&E). Kidney sections from control group showed normal renal morphology (A1–A5). Histological damages after ischemia followed by 1 h of reperfusion including reduction in the size of glomerular tuft, necrosis, medullary vascular congestion and inflammation and cast were observed in I/R (B1–B5) and I/R empty niosome (C1–C5) groups. The administration of crocin-loaded nanoniosomes attenuated these damages compared with untreated animals (Magnification ×400).