Table 1 The effect of niosomal formulation contain crocin on I/R-induced morphological changes followed by 1 h and 24 h of reperfusion.

From: Preparation and evaluation of crocin loaded in nanoniosomes and their effects on ischemia–reperfusion injuries in rat kidney

Groups

Reduction size of

Necrosis

Medullary vascular cogestion

Inflammation

Tubular cast

Control 1 h

0.4

0

0.6

0

0

I/R 1 h

1

0.8*

1.4

1

0

I/R empty noisome

0.8

0.8*

1.8

0.8*

0

I/R crocin noisome

0.4

0.4

1.8

1

0

Control 24 h

0

0

1

0

0

I/R 24 h

1.5**

1

1.8

1.5**

2**

I/R empty 24 h noisome

1.4**

0.6

2.2**

1.6**

2**

I/R crocin 24 h noisome

1

0.5

1**

0.5+

1.5

  1. *P < 0.05, **P < 0.01 versus control; +P < 0.05 versus I/R and I/R + empty niosome group.
Back to article page