Table 2 Univariate and multivariate analysis of LN metastasis risk factors of early gastric cancer.
From: A nomogram to predict risk of lymph node metastasis in early gastric cancer
Univariate analyse | P value | Multivariate analyse | P value | |
|---|---|---|---|---|
OR (95% CI) | OR (95% CI) | |||
Gender | ||||
Female | 1.000 | |||
Male | 1.472 (0.802–2.701) | 0.212 | ||
Age | ||||
≤ 65 | 1.000 | |||
> 65 | 1.417 (0.734–2.736) | 0.299 | ||
CEA (ng/ml) | ||||
≤ 5 | 1.000 | |||
> 5 | 0.955 (0.307–2.970) | 0.936 | ||
CA72-4 (U/ml) | ||||
≤ 7 | 1.000 | |||
> 7 | 1.215 (0.424–3.465) | 0.715 | ||
CA19-9 (U/ml) | ||||
≤ 35 | 1.000 | 1.000 | ||
> 35 | 4.151 (1.287–13.383) | 0.017 | 6.921 (1.316–36.401) | 0.022 |
Tumor size | ||||
≤ 2 cm | 1.000 | 1.000 | ||
> 2 cm | 3.685 (1.777–7.641) | < 0.001 | 4.717 (1.898–11.724) | 0.001 |
Infiltration | ||||
Mucosa | 1.000 | 1.000 | ||
Submucosa | 3.341 (1.649–6.769) | < 0.001 | 2.669 (1.176–6.061) | 0.018 |
Lymphovascular Emboli | ||||
Negative | 1.000 | 1.000 | ||
Positive | 9.855 (4.478–21.688) | < 0.001 | 8.313 (3.295–20.973) | < 0.001 |
Ulcer | ||||
Negative | 1.000 | 1.000 | ||
Positive | 7.911 (3.458–18.095) | < 0.001 | 4.861 (1.931–12.238) | 0.001 |
Histological grade | ||||
Differentiated | 1.000 | 1.000 | ||
Undifferentiated | 2.506 (1.302–4.823) | 0.006 | 2.295 (1.058–4.976) | 0.035 |
Surgery type | ||||
Distant resection | 1.000 | |||
Proximal resection | 1.393 (0.555–3.498) | 0.481 | ||
Total resection | 0.420 (0.094–1.871) | 0.255 | ||
Lauren type | ||||
Intestinal | 1.000 | |||
Diffuse | 0.893 (0.463–1.721) | 0.735 | ||
Mixed | 1.222 (0.579–2.574) | 0.598 | ||
Location | ||||
Upper third | 1.000 | |||
Middle third | 2.072 (0.779–5.506) | 0.144 | ||
Lower third | 1.786 (0.692–4.608) | 0.231 | ||
