Figure 2 | Scientific Reports

Figure 2

From: The effect of blood cells retained in rat livers during static cold storage on viability outcomes during normothermic machine perfusion

Figure 2

Perfusion metrics of 6 h ex-vivo rat liver NMP detailing (A) R, intrahepatic resistance, (B) lactate, (C) oxygen consumption, (D) percent liver weight change, (E) ATP, and (F) energy charge. RT LR flush livers with no SCS (red, n = 4) had the lowest resistance, the lowest lactate levels, and the highest oxygen consumption while no flush livers with SCS (green, n = 4) had the highest resistance and lactate levels. Compared to the cold UW flush livers with SCS (blue, n = 4), RT LR flush livers with SCS (orange, n = 4) had significantly higher lower resistance and lactate levels at 6 h of NMP. RT LR flush livers (red) had significantly higher ATP and EC compared to no flush livers (green) at 6 h of NMP. Stars denote statistical significance (ANOVA, followed by Tukey’s post-hoc test): *0.01 < p < 0.05; **0.001 < p < 0.01; ***0.0001 < p 0.001. Icons represent means and error bars represent standard deviations.

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