Figure 3 | Scientific Reports

Figure 3

From: The effect of blood cells retained in rat livers during static cold storage on viability outcomes during normothermic machine perfusion

Figure 3

Perfusion injury markers of 6 h ex-vivo rat liver NMP detailing (A) AST, (B) ALT, (C) perfusate potassium, and (D–G) gross liver appearance after perfusion. RT LR flush livers with no SCS (red, n = 4) and RT LR flush livers with SCS (orange, n = 4) met transplantable criteria for AST and ALT levels while cold UW flush livers with SCS (blue, n = 4) and no flush livers with SCS (green, n = 4) did not. Grossly, group 1 and 3 livers appeared normal after perfusion while group 2 livers appeared pale from cellular washout and group 4 livers had major areas of infarction and necrosis. Stars denote statistical significance (ANOVA, followed by Tukey’s post-hoc test): *0.01 < p < 0.05; **0.001 < p < 0.01. Icons represent means and error bars represent standard deviations.

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