Table 2 Risk of ocular motor cranial nerve palsy according to the presence of metabolic syndrome and its components.

From: Association between metabolic syndrome and incidence of ocular motor nerve palsy

 

N

Event

Person-years

Incidence ratea

HR (95% CI)

Model 1b

Model 2c

Model 3d

MetS

No

3,216,838

3713

26,508,066.95

0.14007

1 (Ref.)

1 (Ref.)

1 (Ref.)

Yes

851,004

2122

6,910,285.61

0.30708

2.193 (2.079,2.313)

1.427 (1.35,1.507)

1.351 (1.273,1.434)

WC (cm)

M < 90, F < 85

3,269,478

4175

26,894,123.84

0.15524

1 (Ref.)

1 (Ref.)

1 (Ref.)

M ≥ 90, F ≥ 85

798,364

1660

6,524,228.72

0.25444

1.639 (1.548,1.735)

1.237 (1.167,1.31)

1.239 (1.17,1.313)

Serum triglycerides (mmol/L)

Low (< 1.70)

2,639,483

3106

21,717,870.01

0.14302

1 (Ref.)

1 (Ref.)

1 (Ref.)

High (≥ 1.70)

1,428,359

2729

11,700,482.55

0.23324

1.631 (1.549,1.717)

1.245 (1.182,1.311)

1.183 (1.121,1.248)

Serum HDL-C (mmol/L)

High (M ≥ 1.04, F ≥ 1.30)

3,630,818

4754

29,857,072.14

0.15923

1 (Ref.)

1 (Ref.)

1 (Ref.)

Low (M < 1.04, F < 1.30)

437,024

1081

3,561,280.41

0.30354

1.905 (1.783,2.035)

1.296 (1.211,1.386)

1.242 (1.16,1.329)

BP

Normal

2,262,740

2305

18,733,463.27

0.12304

1 (Ref.)

1 (Ref.)

1 (Ref.)

Highe

1,805,102

3530

14,684,889.28

0.24038

1.955 (1.855,2.06)

1.179 (1.115,1.247)

1.126 (1.063,1.192)

Plasma fasting glucose

Normal

2,791,821

3038

23,050,149.11

0.1318

1 (Ref.)

1 (Ref.)

1 (Ref.)

Highf

1,276,021

2797

10,368,203.44

0.26977

2.049 (1.946,2.157)

1.462 (1.387,1.541)

1.428 (1.354,1.506)

Smoking

Non

2,415,745

3177

19,904,128.18

0.15962

1 (Ref.)

1 (Ref.)

1 (Ref.)

Ex

585,736

1159

4,790,690.26

0.24193

1.519 (1.42,1.625)

1.070 (0.99,1.156)

1.094 (1.011,1.183)

Current

1,066,361

1499

8,723,534.12

0.17183

1.079 (1.015,1.147)

1.051 (0.977,1.131)

1.104 (1.024,1.19)

Drinking

Non

2,093,893

3289

17,156,972.09

0.1917

1 (Ref.)

1 (Ref.)

1 (Ref.)

Mild

1,650,016

2079

13,612,474.28

0.15273

0.797 (0.755,0.842)

0.887 (0.835,0.943)

0.872 (0.82,0.928)

Heavy

323,933

467

2,648,906.18

0.1763

0.921 (0.836,1.015)

0.865 (0.782,0.958)

0.832 (0.75,0.923)

Physical activity

No

3,329,743

4623

27,336,646.48

0.16911

1 (Ref.)

1 (Ref.)

1 (Ref.)

Yes

738,099

1212

6,081,706.08

0.19929

1.178 (1.105,1.254)

1.015 (0.952,1.081)

1.013 (0.95,1.079)

  1. N number, HR hazard ratio, CI confidence interval, MetS metabolic syndrome, WC waist circumference, M males, F females, HDL-C high-density lipoprotein cholesterol, BP blood pressur.
  2. aOcular motor incidence per 1,000 person-years.
  3. bModel 1 was unadjusted.
  4. cModel 2 was adjusted for age and sex.
  5. dModel 3 was adjusted for age, sex, smoking status, alcohol consumption, and physical activity.
  6. eSystolic BP ≥ 130 mmHg, diastolic BP ≥ 85 mmHg, or treatment with antihypertensive agents.
  7. fPlasma fasting glucose ≥ 5.55 mmol/L or the use of hypoglycemic agents.
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