Figure 6 | Scientific Reports

Figure 6

From: Coordination of retrotransposons and type I interferon with distinct interferon pathways in dermatomyositis, systemic lupus erythematosus and autoimmune blistering disease

Figure 6

Scheme of retrotransposon-mediated IFN responses in SLE and DM. (A) The activation level of the IFN production pathway in patients with SLE and DM differed. Genes with significantly elevated and suppressed expression compared with those in the control group are highlighted in red and blue, respectively. (B) The correlation among genes. Genes with significantly elevated and suppressed expression compared with those in the control are highlighted in red and blue, respectively. The connected lines show the significant positive correlations between two genes calculated by a nonparametric Spearman’s rank correlation test. TE; transposable element, nRTK;: nonreceptor tyrosine kinase, TF; transcription factor.

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