Table 2 Level 2, 3, and 4 alterations in patients with CUP.
From: Real-world data analysis of patients with cancer of unknown primary
Alteration level | Alteration | N | Histology |
|---|---|---|---|
Level 1 | NTRK1-LMNA | 1 | Adenocarcinoma |
Level 2 | BRAF V600E | 1 | Carcinoma NOS |
BRCA2 E3167D | 1 | Adenocarcinoma | |
BRCA2 I1859Kfs*3 | 1 | Squamous cell carcinoma | |
Total | 3 | ||
Level 3 | NRAS G12D | 1 | Adenocarcinoma |
PIK3CA E545K | 2 | Squamous cell carcinoma | |
ATM Q754* | 1 | Carcinoma NOS | |
ATM K2749I | 1 | Carcinoma NOS | |
ERBB2 S310F | 1 | Adenocarcinoma | |
Total | 6 | ||
Level 4 | BRAF G469A, NF1 R1362* | 1 | Adenocarcinoma |
KRAS G12A | 1 | Neoplasms NOS | |
KRAS G12Sa | 1 | Adenocarcinoma | |
PTEN Q17* | 2 | Adenocarcinoma, squamous cell carcinoma | |
Total | 5 |
