Table 1 Body and tissue weights, and cardiac myocyte dimensions of mice with and without tumors.

From: Cardiac myocyte intrinsic contractility and calcium handling deficits underlie heart organ dysfunction in murine cancer cachexia

 

Absolute measurement

Percent body weighta

Control

Tumor

Control

Tumor

Initial Body Weight (g)

25.3 ± 0.5

25.3 ± 1.0

  

Final Body Weight (g)

27.8 ± 0.6

24.4 ± 1.2*

  

Body Weight Change (g)

2.5 ± 0.4

 − 0.9 ± 0.8**

9.8 ± 1.5

 − 3.4 ± 3.3**

Tumor-Free Body Weight Change (g)

2.5 ± 0.4

 − 2.4 ± 0.9***

9.8 ± 1.5

 − 9.2 ± 3.7 ***

Tibialis Anterior (mg)

50.2 ± 1.7

36.4 ± 3.5**

0.18 ± 0.01

0.15 ± 0.01**

Heart Weight (mg)

126.5 ± 4.0

108.5 ± 3.7**

0.46 ± 0.01

0.45 ± 0.01

Tibia Length (mm)

17.1 ± 0.2

16.9 ± 0.1

  

Heart Weight/Tibia Length (mg/mm)

7.4 ± 0.2

6.4 ± 0.2**

  

Cardiac Myocyte Length (nm)

119.4 (107.2–135.8)

121.4 (110.1–135.2)

  

Cardiac Myocyte Width (nm)

25.6 (19.8–30.4)

18.0 (14.9–21.9)**

  

Tumor Weight (g)

 

1.5 ± 0.1

 

6.2 ± 0.7

  1. N = 9 mice per group; data are mean ± SEM or median (IQR); *P < 0.05, **P < 0.01, ***P < 0.001 compared to control.
  2. aCalculated as: (body weight change/initial body weight) × 100 or (tissue weight/final body weight including tumor) × 100.
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