Table 3 Molecular profiles in 90 gastric cancers.

From: Comparable genetic alteration profiles between gastric cancers with current and past Helicobacter pylori infection

Characteristic

H. pylori infection status

p value

Current

Past

N (%)

N (%)

Oncogene point mutations in hotspots

Yes

4 (7.3)

7 (20.0)

0.100

No

51 (92.7)

28 (80.0)

 

Gene amplification of oncogenes

Yes

7 (12.7)

3 (8.6)

0.735

No

48 (87.3)

32 (91.4)

 

Oncogene activation (either or both point mutations in hotspots and gene amplification)

Yes

11 (20.0)

10 (28.6)

0.444

No

44 (80.0)

25 (71.4)