Table 3 Molecular profiles in 90 gastric cancers.
Characteristic | H. pylori infection status | p value | |
|---|---|---|---|
Current | Past | ||
N (%) | N (%) | ||
Oncogene point mutations in hotspots | |||
Yes | 4 (7.3) | 7 (20.0) | 0.100 |
No | 51 (92.7) | 28 (80.0) | |
Gene amplification of oncogenes | |||
Yes | 7 (12.7) | 3 (8.6) | 0.735 |
No | 48 (87.3) | 32 (91.4) | |
Oncogene activation (either or both point mutations in hotspots and gene amplification) | |||
Yes | 11 (20.0) | 10 (28.6) | 0.444 |
No | 44 (80.0) | 25 (71.4) | |