Table 3 Mean ± SD of CEUS evaluation of the left kidney in bitches with mammary carcinoma treated (TG) or not treated (CG) with carprofen 4.4 mg/kg/day for 90 days and evaluated for 6 months.

From: Ultrasonographic assessment of renal perfusion in bitches with mammary carcinoma treated with long-term carprofen

Variable

Moment

CG

TG

P-Group

P-Moment

P-Interaction

CortPI (%)

M0

22.8 ± 7.99

21.3 ± 1.88

0.2619

0.4152

0.7322

M1

23.1 ± 5.25

22.3 ± 9.14

M2

25.4 ± 8.42

26.1 ± 6.11

M3

21.1 ± 3.6

25.2 ± 4.36

M4

23.7 ± 2.73

27.4 ± 19.1

M5

27.4 ± 11.8

23.3 ± 6.6

M6

23.7 ± 12.6

40.3 ± 36.9

CortTmT (s)

M0

29.3 ± 16.2

19.7 ± 1.77

0.3399

0.5822

0.533

M1

24.9 ± 4.42

25.6 ± 14.5

M2

25.3 ± 9.76

30.7 ± 13.3

M3

24.1 ± 3.95

25.5 ± 10.6

M4

20.5 ± 7.56

27.1 ± 7.24

M5

22.1 ± 13.9

35.0 ± 19.3

M6

29.2 ± 11.2

33.0 ± 9.93

CortAUC

M0

963 ± 1038

548 ± 80.1

0.2695

0.6137

0.7469

M1

734 ± 219

815 ± 752

M2

786 ± 381

1004 ± 555

M3

655 ± 152

892 ± 476

M4

545 ± 194

863 ± 481

M5

734 ± 659

1024 ± 510

M6

815 ± 472

1319 ± 862

(a) Cort (%/s)

M0

1.80 ± 0.83

1.86 ± 0.94

0.5991

0.7909

0.5253

M1

1.68 ± 0.39

1.7 ± 0.79

M2

2.09 ± 1.13

1.89 ± 0.95

M3

1.75 ± 0.63

2.31 ± 0.76

M4

1.87 ± 0.71

1.91 ± 0.93

M5

1.93 ± 0.55

1.73 ± 0.78

M6

1.37 ± 1.12

2.30 ± 1.80

(b) Cort (%/s)

M0

2.22 ± 1.36

3.57 ± 1.69

0.911

0.3934

0.4017

M1

2.58 ± 1.25

3.25 ± 2.28

M2

3.32 ± 2.38

3.14 ± 2.15

M3

2.22 ± 1.04

2.76 ± 2.06

M4

4.9 ± 3.36

3.98 ± 4.99

M5

5.69 ± 2.59

2.38 ± 2.7

M6

2.95 ± 1.45

2.66 ± 1.99

MedPI (%)

M0

22.1 ± 3.71

25.0 ± 10.3

0.0544

0.5365

0.1343

M1

24.8 ± 8.75

25.4 ± 8.41

M2

24.9 ± 6.1

30.8 ± 7.01

M3

18.2 ± 5.18

30.3 ± 7.64

M4

24.2 ± 8.31

23.0 ± 11.6

M5

32.8 ± 5.41

26.2 ± 9.45

M6

31.6 ± 9.29

27.2 ± 8.54

MedTp (s)

M0

46.3 ± 14.2

52.8 ± 4.29

0.8617

0.6705

0.9907

M1

51.9 ± 8.82

51.8 ± 21.7

M2

46.1 ± 22.5

47.3 ± 12.6

M3

48.4 ± 16.9

48.7 ± 14.9

M4

52.7 ± 7.07

48.8 ± 9.69

M5

59.8 ± 4.05

54.8 ± 9.7

M6

57.7 ± 29.7

53.6 ± 11.1

MedTmT (s)

M0

58.8 ± 15.4

70.2 ± 0.19

0.9923

0.7301

0.9775

M1

65.7 ± 10.1

63.2 ± 21.9

M2

60.9 ± 27.2

57.0 ± 14.1

M3

62.4 ± 15.0

59.9 ± 17.3

M4

63.5 ± 7.08

61.6 ± 10.7

M5

70.0 ± 6.42

72.5 ± 20.5

M6

64.1 ± 26.1

64.2 ± 11.0

MedAUC

M0

1267 ± 413

1573 ± 365

0.5217

0.6217

0.6358

M1

1602 ± 471

1568 ± 780

M2

1618 ± 1116

1579 ± 478

M3

1171 ± 458

1780 ± 848

M4

1386 ± 474

1471 ± 802

M5

1964 ± 44.3

1781 ± 511

M6

2232 ± 1700

1694 ± 912

(a) Med (%/s)

M0

0.54 ± 0.25

0.48 ± 0.23

0.7263

0.1773

0.6626

M1

0.49 ± 0.18

0.52 ± 0.13

M2

0.89 ± 0.85

0.67 ± 0.17

M3

0.41 ± 0.16

0.65 ± 0.19

M4

0.45 ± 0.13

0.47 ± 0.22

M5

0.55 ± 0.13

0.50 ± 0.24

M6

0.67 ± 0.45

0.52 ± 0.17

(b) Med (%/s)

M0

2.07 ± 0.85

1.41 ± 0.26

0.9171

0.7117

0.6999

M1

2.17 ± 1.29

2.43 ± 1.17

M2

2.56 ± 2.45

3.63 ± 1.56

M3

1.41 ± 0.60

3.22 ± 1.89

M4

2.36 ± 1.08

2.20 ± 1.67

M5

3.44 ± 1.48

2.20 ± 1.90

M6

2.77 ± 0.84

2.66 ± 0.57

  1. CortPI: cortical peak intensity; CortTmT: cortical mean time of transmission; CortAUC: cortical mean area under the curve; (a) Cort: cortical wash-in slope; (b) Cort; cortical wash-out slope; MedPI: medullary peak intensity; MedTp: medullary time until peak intensity; MedTmT: medullary mean time of transmission; MedAUC: medullary area under the curve; (a) Med: medullary wash-in slope; (b) Med: medullary wash-out slope.