Figure 6
From: Ketogenic Diet as a potential treatment for traumatic brain injury in mice
Study timeline. Animals were exposed to mTBI or sham and checked for ketone bodies in the blood at days 0, 3, 7 and 30. Mice were then fed KD/SD for 3, 7, or 30 days. Behavioral tests to assess behavior and cognitive abilities were carried out at 7 and 30 days following mTBI in separate cohorts. Western blot analysis to assess changes in SIRT1 levels following mTBI and diets management was performed at 7 and 30 days post-mTBI. Immunohistochemical staining to evaluate neurodegeneration and neuroinflammation was performed at 30 days following the mTBI challenge.
