Figure 3 | Scientific Reports

Figure 3

From: Effects of tumor necrosis factor-α inhibition on kidney fibrosis and inflammation in a mouse model of aristolochic acid nephropathy

Figure 3

Effect of etanercept on kidney fibrosis. (a) Relative renal mRNA expression of Col1a1, Col3a1, and TGF-β (n = 7–8). (b) Representative images of kidneys stained with picrosirius red (upper panel, original magnification, × 40, bar, 200 μm; lower panel, original magnification, × 200, bar, 50 μm), and quantitative analysis of kidney fibrotic area (n = 7–8). Values are means ± SEM. * P < 0.05, *** P < 0.001. Ctrl, control; AA, aristolochic acid; ETN, etanercept; Col, collagen; TGF, transforming growth factor.

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