Figure 8
Effect of i.v. or intra-thymic injection of α-GalCer on NKT cells in NOD.Va14tg mice. Flow cytometric comparison of the effects of i.v. injection with PBS (A) or α-GalCer (B) on thymic, hepatic and splenic NKT cell proportions, subsets (A,B) and absolute numbers (C) in NOD.Va14tg /1 mice (**P < 0.01; ****P < 0.0001; Mann–Whitney U Test; n = 10 mice/group). (D) Flow cytometric comparison of the effects of intrathymic injection of α-GalCer on absolute numbers in NOD.Va14tg mice compared to untreated mice. (*P < 0.05; **P < 0.01; Mann–Whitney U Test; n = 5–7 female mice/group). Filled circles represent PBS treated mice; filled triangles represent α-GalCer-treated mice.
