Table 1 Baseline characteristics of study participants with type-B acute aortic syndrome.
From: Predictors of hypoxemia in type-B acute aortic syndrome: a retrospective study
Total (N = 224) | Hypoxemia (N = 53) | Non-hypoxemia (N = 171) | p value | |
|---|---|---|---|---|
Age | 70.5 ± 13.8 | 67.3 ± 14.5 | 71.5 ± 13.5 | 0.057 |
Male | 140 (62.5) | 44 (83.0) | 96 (56.1) | < 0.001 |
Body mass index (kg/m2) | 23.4 (21.0–25.9) | 24.8 (23.4–27.4) | 22.9 (20.5–25.3) | < 0.001 |
Obesity | 74 (33.0) | 25 (47.2) | 49 (28.7) | 0.018 |
Current smoker | 65 (29.0) | 22 (41.5) | 43 (25.1) | 0.022 |
Hypertension | 176 (78.6) | 44 (83.0) | 132 (77.2) | 0.45 |
Diabetes mellitus | 18 (8.0) | 3 (5.7) | 15 (8.8) | 0.77 |
Dyslipidemia | 71 (31.7) | 22 (41.5) | 49 (28.7) | 0.088 |
Thoracic/abdominal aortic aneurysm | 56 (25.0) | 11 (20.8) | 45 (26.3) | 0.47 |
Medications on admission | ||||
Antiplatelet agent | 34 (15.2) | 5 (9.4) | 29 (17.0) | 0.27 |
Anticoagulant | 7 (3.1) | 2 (3.8) | 5 (2.9) | 0.67 |
Antihypertensive treatment | 115 (51.3) | 24 (45.3) | 91 (53.2) | 0.35 |
Vital signs on admission | ||||
Systolic blood pressure (mmHg) | 160 (145–188) | 173 (148–191) | 163 (144–184) | 0.13 |
Diastolic blood pressure (mmHg) | 85 (74–98) | 88 (74–108) | 84 (74–96) | 0.37 |
Heart rate (/min) | 77 ± 13 | 78 ± 12 | 76 ± 14 | 0.42 |
Laboratory data on admission | ||||
White blood cell (/µL) | 9100 (7275–11,625) | 9799 (8200–13,200) | 8800 (6800–10,800) | 1.5 × 10–3 |
Hemoglobin (g/dL) | 13.3 (12.0–14.8) | 14.2 (12.7–15.1) | 13.2 (11.9–14.4) | 0.068 |
D-dimer (µg/mL) | 11.1 (5.8–25.9) | 14.5 (6.5–37.2) | 6.1 (2.3–13. 8) | < 0.001 |
Creatinine (mg/dL) | 0.82 (0.65–1.12) | 1.03 (0.82–1.34) | 0.79 (0.63–1.04) | < 0.001 |
CRP (mg/dL) | 0.22 (0.07–0.75) | 0.23 (0.08–0.42) | 0.22 (0.07–0.82) | 0.59 |
BNP (pg/mL) | 39 (19–87) | 44.5 (22–74) | 37 (19–90) | 0.93 |
CT findings on admission | ||||
Patent false lumen | 92 (41.1) | 33 (62.3) | 59 (34.5) | < 0.001 |
IMH | 132 (58.9) | 20 (37.7) | 112 (65.5) | < 0.001 |
Maximum aneurysm diameter (mm) | 37 (33, 41) | 38 (35, 40) | 36 (32, 41) | 0.14 |
Pleural effusion | 45 (20.1) | 15 (28.3) | 20 (17.5) | 0.12 |
COPD | 34 (15.2) | 5 (9.4) | 29 (17.0) | 0.064 |
Interstitial pneumonia | 4 (1.8) | 0 (0.0) | 4 (2.3) | 0.58 |
After hospitalization | ||||
Minimum PaO2/FiO2 ratio | 267 (209–328) | 160 (133–175) | 305 (246–346) | < 0.001 |
Timing of hypoxemia (hours) | – | 38 (23, 58) | – | – |
Peak CRP level (mg/dL) | 10.5 (6.8,-5.7) | 13.8 (10.5–23.3) | 9.1 (6.0–13.1) | < 0.001 |
Timing of peak CRP level (days) | 4 (3, 6) | 3 (3, 5) | 4 (3, 6) | 0.43 |
ICU stay (days) | 5 (3–8) | 7 (5–10) | 5 (3–7) | < 0.001 |
Hospital stay (days) | 16 (13–22) | 20 (14–26) | 16 (12.5–21) | 0.039 |
