Figure 1

Heatmap of Spearman’s rank correlation coefficients between metabolites associated with lowly and highly sensitized asthma (A) and metabolic pathways of metabolites associated with atopic and non-atopic asthma (B). Red color represents positive correlations; blue color represents negative correlations; red arrow represents increase; blue arrow represents decrease. + symbol means a P-value < 0.05; ++ symbol means a P-value < 0.01.