Table 1 Comparison of the clinical and epidemiologic characteristics between lowly and highly sensitized asthma, and healthy controls.
Characteristics | Asthma | P-value | Asthma | Controls | P-value | |
|---|---|---|---|---|---|---|
Non-atopic, lowly sensitized (n = 15) | Atopic, highly sensitized (n = 13) | Total (n = 28) | Healthy (n = 25) | |||
Age (yr) | 3.7 ± 0.6 | 3.5 ± 0.7 | 0.374 | 3.6 ± 0.7 | 3.6 ± 0.7 | 0.887 |
Sex, male | 9 (60.0%) | 10 (76.9%) | 0.435 | 19 (67.9%) | 15 (60.0%) | 0.552 |
BMI-for-age | 16.0 ± 1.5 | 16.8 ± 1.6 | 0.199 | 16.3 ± 1.6 | 15.9 ± 2.1 | 0.519 |
Maternal atopy | 5 (33.3%) | 8 (61.5%) | 0.136 | 13 (46.4%) | 8 (32.0%) | 0.284 |
Passive smoking | 6 (40.0%) | 9 (69.2%) | 0.122 | 15 (53.6%) | 9 (36.0%) | 0.200 |
Breastfeeding > 6 mo* | 0.755 | 0.074 | ||||
Exclusive | 5 (33.3%) | 3 (23.1%) | 8 (28.6%) | 9 (36.0%) | ||
Partial | 5 (33.3%) | 4 (30.8%) | 9 (32.1%) | 13 (52.0%) | ||
Formula | 5 (33.3%) | 6 (46.2%) | 11 (39.3%) | 3 (12.0%) | ||
Allergen-specific IgE, kU/L | ||||||
D. pteronyssinus | 2.0 ± 1.2 | 42.0 ± 37.4 | < 0.001 | 20.6 ± 32.3 | 0.4 ± 0.3 | 0.001 |
D. farinae | 1.0 ± 1.8 | 29.5 ± 36.1 | < 0.001 | 14.2 ± 28.1 | 0.2 ± 0.3 | 0.001 |
Total serum IgE, kU/L | 60.5 ± 71.4 | 401.3 ± 345.9 | < 0.001 | 218.7 ± 292.9 | 38.3 ± 37.1 | 0.001 |
