Table 3 Secondary outcomes and neonatal morbidities.

From: RAM cannula with Cannulaide versus Hudson prongs for delivery of nasal continuous positive airway pressure in preterm infants: an RCT

Secondary outcomes

RAM cannula (n = 112)

Hudson prong (n = 117)

RR/mean difference (95% CI)

p value

Need for mechanical ventilation in first 72 h of agea

11 (9.8)

13 (11.4)

0.97 (0.86–1.09)

0.75

Change of interfacea

1 (0.82)

8 (6.3)

0.94 (0.89–0.99)

0.02

Duration of CPAP (h)b

20 (12–38)

14 (7–24)

9.3 (1.7–17)

0.04

Infants who remained on CPAP by 3 days of agea

11 (9.8)

10 (8.5)

0.87 (0.38–1.96)

0.74

Duration of O2 (days)b

3 (2–6)

3 (2–5)

− 0.13 (− 2.2 to 2)

0.8

CPAP failure (MV < 72 h/change in nasal interface)a

12 (10.7)

21 (17.9)

0.91 (0.82–1)

0.12

Culture positive sepsisa

8 (7.1)

17 (14.5)

0.92 (0.84–1)

0.07

Patent ductus arteriosusa

3 (2.7)

13 (11.1)

0.91 (0.85–0.98)

0.01

Necrotizing enterocolitisa

4 (3.6)

6 (5.1)

0.98 (0.93–1)

0.56

IVH grade 3 or morea

0

1 (0.9)

0.99 (0.97–1)

0.32

Cystic PVLa

0

1 (0.9)

0.99 (0.97–1)

0.32

ROP needing lasera

0

3 (2.6)

0.97 (0.94–1)

0.09

Supplemental O2 at 28 daysa

4 (3.6)

5 (4.3)

0.99 (0.97–1)

0.76

Air leaksa

3 (2.7)

1 (0.9)

1 (0.98–1.05)

0.3

Mortalitya

1 (0.9)

4 (3.4)

0.97 (0.93–1.03)

0.19

Transfers to other hospitala

3 (2.67)

7 (6)

0.45 (0.12–1.69)

0.24

Discharge from hospitala

108 (96.4)

106 (90.5)

1.06 (0.99–1.14)

0.07

Length of hospital stay (days)c

17.6 ± 12.8

16.7 ± 11.9

− 0.3 (− 3.3 to 2.7)

0.59

Weight at discharge (g)c

1590 ± 220

1587 ± 265

6.2 (− 55 to 66)

0.92

Length at discharge (cms)c

42.8 ± 2.5

42 ± 2.9

− 0.24 (− 0.92 to 0.43)

0.35

Head circumference at discharge (cms)c

30.1 ± 1.6

30.2 ± 1.7

0.07 (− 0.3 to 0.49)

0.64

  1. MV mechanical ventilation, IQR interquartile range, CPAP continuous positive airway pressure.
  2. an (%).
  3. bMedian (inter quartile range).
  4. cMean (standard deviation).