Figure 7
From: Temperature responsive chromatography for therapeutic drug monitoring with an aqueous mobile phase
Chromatograms of antiepileptic drug and anti-arrhythmic drug with serum proteins using crosslinked PNIPAAm modified-bead packed columns. (A) Carbamazepine, (B) phenytoin, (C) lamotrigine, (D) quinidine, (E) propafenone, and (F) disopyramide. Mobile phase was 10 mM CH3COONH4 (pH 6.75) buffer solution for carbamazepine, phenytoin, lamotrigine, and disopyramide, and 10 mM CH3COONH4 buffer solution (pH 4.80) for quinidine and propafenone. The mobile phase flow rate was 1.0 mL/min.
