Table 1 Body and thyroid weights.

From: Single neonatal irradiation induces long-term gene expression changes in the thyroid gland, which may be involved in the tumorigenesis

Group

Treatment

Age of necropsy

Body weight (g)

Thyroid weight (mg)

Thyroid weight (mg/kg b.w.)

Experiment 1

Control

ShamX at 5–6 days old

9 w.o

380 ± 8.9

18 ± 1.8

48 ± 4.7

1w1.5 Gy

1.5 Gy at 5–6 days old

9 w.o

390 ± 10.2

19 ± 1.3

49 ± 3.2

1w3Gy

3 Gy at 5–6 days old

9 w.o

355 ± 7.8

17 ± 1.5

48 ± 5.0

1w6Gy

6 Gy at 5–6 days old

9 w.o

330 ± 19.9

14 ± 1.5

42 ± 1.9

1w12Gy

12 Gy at 5–6 days old

9 w.o

291 ± 22.9*

12 ± 1.0*

43 ± 3.4

Experiment 2

Control

ShamX at 5–6 days old

17 w.o

607 ± 19.3

29 ± 2.2

48 ± 4.0

1w12Gy

12 Gy at 5–6 days old

17 w.o

446 ± 38.2*

15 ± 1.9**

34 ± 5.3

2w12Gy

12 Gy at 2 weeks old

17 w.o

557 ± 23.5

24 ± 2.1

42 ± 1.9

4w12Gy

12 Gy at 4 weeks old

17 w.o

576 ± 38.8

21 ± 0.5

37 ± 2.3

8w12Gy

12 Gy at 8 weeks old

17 w.o

541 ± 11.0

24 ± 1.6

45 ± 3.0

Experiment 3

Control

ShamX at 5–6 days old

29 w.o

692 ± 11.5

21 ± 3.9

30 ± 5.5

1w12Gy

12 Gy at 5–6 days old

29 w.o

522 ± 42.6

15 ± 1.3

29 ± 3.9

IDD

IDD

29 w.o

298 ± 6.9**

293 ± 29**

993 ± 113**

1w12Gy-IDD

12 Gy at 5–6 days old + IDD

29 w.o

249 ± 15.6**

147 ± 21**

592 ± 65**

  1. The numbers of rats in each group were 6 rats/group in Experiment 1; 5 rats/group in Experiment 2; 4, 3, 7, and 8 rats in Control, 1w12Gy, IDD, and 1w12Gy-IDD, respectively, in Experiment 3.
  2. *, and ** indicate significant differences from each control (*p < 0.05; **p < 0.01).