Figure 7 | Scientific Reports

Figure 7

From: INTS8 is a therapeutic target for intrahepatic cholangiocarcinoma via the integration of bioinformatics analysis and experimental validation

Figure 7

MMR genes and DNA methylation genes involved in CHOL. (A) A total of 3 MMR genes were detected in CHOL. The right-angled triangle in the lower left corner represents the Pearson’s correlation between INTS8 and MMR gene expression. The right-angled triangle in the upper right corner represents the p value; *p < 0.05, **p < 0.01 and ***p < 0.001 show significant differences. (B) Circle diagram showing the association between INTS8 and DNMTs. The first circle from outer to inner is the abbreviation of cancers. The second circle is the specific DNMTs, with DNMT1 (red), DNMT2 (blue), DNMT3A (green), and DNMT3B (purple). The third circle is the correlation coefficient. Green represents negative correlations; Red represents positive correlations. The fourth circle is the p value. And the fifth circle is the specific value of the correlation coefficient and p.

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