Table 3 Comparison of laboratory findings between SLE patients with and without thrombotic events.

From: Risk factors for thrombotic events in Korean patients with systemic lupus erythematosus

 

All (N = 259)

Thrombotic events (n = 27)

No event (n = 232)

P-value

Laboratory findings

White blood cells, 1,000/mm3

4.88 ± 2.66

5.37 ± 2.43

4.82 ± 2.68

0.148

Lymphocytes, mm3

1.16 ± 0.66

1.26 ± 0.62

1.15 ± 0.64

0.373

Hemoglobin, g/dL

11.3 ± 6.67

11.1 ± 2.59

11.4 ± 6.98

0.459

Platelet, × 103/μL

183.1 ± 96.7

179.7 ± 108.2

183.5 ± 95.5

0.885

ESR, mm/h

48.5 ± 34.1

40.0 ± 29.9

49.7 ± 34.5

0.200

CRP, mg/dL

1.89 ± 2.45

0.09 ± 1.47

1.22 ± 2.54

0.241

Serum creatinine, mg/dL

0.78 ± 0.85

1.00 ± 1.05

0.75 ± 0.82

0.074

Total cholesterol, mg/dL

170.7 ± 54.9 (n = 249)

194.2 ± 64.4 (n = 27)

167.9 ± 53.2 (n = 222)

0.046

LDL-cholesterol, mg/dL

97.7 ± 36.7 (n = 187)

105.3 ± 36.8 (n = 20)

96.7 ± 36.7 (n = 167)

0.335

Autoantibodies (%)

Anti-nuclear

227 (91.2)

23 (88.5)

204 (91.5)

0.608

Anti-Sm

78 (30.2)

7 (25.9)

71 (30.7)

0.607

Anti-dsDNA

147 (56.8)

13 (48.1)

134 (57.8)

0.340

Anti-RNP

109 (42.2)

9 (33.3)

100 (43.3)

0.322

Anti-Ro/SS-A

160 (61.8)

18 (66.7)

142 (61.2)

0.581

Anti-La/SS-B

73 (28.2)

9 (33.3)

64 (27.6)

0.530

aPL

54 (21.1)

10 (37.0)

44 (19.2)

0.032

Complement level (%)

Decreased C3 level

178 (68.1)

16 (59.3)

162 (69.8)

0.262

Decreased C4 level

124 (47.9)

11 (40.7)

113 (48.7)

0.282

  1. Except where otherwise indicated, data are presented as the mean ± standard deviation.
  2. aPL, anti-phospholipid antibody; ESR, erythrocyte sedimentation rate; CRP, C-reactive protein; SLE, systemic lupus erythematosus.