Figure 5 | Scientific Reports

Figure 5

From: Persimmon-derived tannin has antiviral effects and reduces the severity of infection and transmission of SARS-CoV-2 in a Syrian hamster model

Figure 5

Effect of pre-administration of persimmon-derived tannin on virus titers, viral load, and inflammatory-related gene expression in the lung of contact hamsters cohoused with a virus-inoculated donor. (a) Virus titers were measured by plaque assay. The uppermost lobe of the right lung was used and the plaque-forming units (pfu) per lobe were calculated. (b) Viral load was measured by quantitative PCR. (c) Expressions of Il1b, Il6, Tnf, Ifng, and LOC101824794 (interferon alpha-9-like) were measured by quantitative PCR. RNA extracted from the right lung was used and normalized to Gapdh expression. Data are shown as the mean ± SEM (control group; n = 4, tannin group, n = 4). ND, not detected. *p < 0.05, **p < 0.01, ***p < 0.001.

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