Figure 3

Pie charts for the cumulative number of released virions and TIPs 100 days post infection. Increasing the MOI of tiRNA (T) increases the cumulative number of released TIPs and reduces the total number of released particles (virion+TIP) compared with the control. Red and blue indicate the number of virions and TIPs, respectively, while white shows the difference between the total number of released virions in the control (tiRNA-free) case with the number of released particles (virion+TIP) in the presence of treatment. This figure is plotted by averaging over 250 simulations using parameter values from Table 1 with \(b_a=1\) and \(b_r=1\). The initial condition for the MOIs of \(\hbox {V}=m\), \(\hbox {T}=n\) is (+)\(\hbox {RNA}^{\text{cyt}}=m\), (+)\(\hbox {tiRNA}^{\text{cyt}}=n\), and \(\hbox {Cp}=180(m+n)\).