Table 1 Demographic and medical characteristic of patients (N = 371).
Characteristic | Mean (SD) or N (%) | Bivariate analysis | ||
|---|---|---|---|---|
Alive n = 134 (36.1%) | Died n = 237 (63.9%) | p-value | ||
Age | 38.3 (13) | 36.4 (12.1) | 39.3 (13.3) | 0.043 |
Gender | 0.189 | |||
Female | 177 (47.7) | 70 (40) | 107 (60) | |
Male | 194 (52.3) | 64 (33) | 130 (67) | |
Relapse | 0.050 | |||
Yes | 69 (18.6) | 18 (26.1) | 51 (73.9) | |
No | 302 (81.4) | 116 (38.4) | 186 (61.6) | |
White blood cell count | 0.060 | |||
WBC < 30 × \({10}^{9}\)/L | 240 (65) | 95 (40) | 145 (60) | |
WBC \(\ge 30 \times {10}^{9}\)/L | 131 (35) | 39 (30) | 90 (70) | |
AML classification (FAB) | 0.010 | |||
M0 | 52 (16) | 8 (15.4) | 44 (84.6) | |
M0–M1 | 3 (0.9) | 1 (33.3) | 2 (66.7) | |
M1 | 38 (11.7) | 12 (31.6) | 26 (68.4) | |
M1–M2 | 76 (23.5) | 24 (31.6) | 52 (68.4) | |
M2 | 50 (15.4) | 21 (42) | 29 (58) | |
M3 | 24 (7.4) | 15 (62.5) | 9 (37.5) | |
M4 | 44 (13.6) | 21 (47.7) | 23 (52.3) | |
M4–M5 | 19 (5.9) | 6 (31.6) | 13 (68.4) | |
M5 | 14 (4.3) | 4 (28.6) | 10 (71.4) | |
M6 | 3 (0.9) | 0 | 3 (100) | |
M7 | 1 (0.3) | 1 (100) | 0 | |
Cytogenetic prognosis | 0.027 | |||
Poor | 31 (16.3) | 6 (19.4) | 25 (80.7) | |
Intermediate | 114 (60) | 48 (42.1) | 66 (57.9) | |
Favorable | 45 (23.7) | 22 (49) | 23 (51) | |
Type of induction therapy | 0.015 | |||
DNR | 229 (62) | 85 (37.1) | 144 (62.9) | |
IDA | 50 (13.6) | 26 (52) | 24 (48) | |
Doxo | 42 (11.4) | 13 (31) | 29 (69) | |
Other | 48 (13) | 10 (20.8) | 38 (79.2) | |
Complications after chemotherapy | ||||
Febrile neutropenia | 0.069 | |||
Yes | 101 (27.2) | 44 (43.6) | 57 (56.4) | |
No | 270 (72.8) | 90 (33.3) | 180 (66.7) | |
Sepsis | 0.060 | |||
Yes | 93 (25.1) | 26 (28) | 67 (72) | |
No | 278 (74.9) | 108 (39) | 170 (61) | |
Aspergillosis | 0.146 | |||
Yes | 70 (18.9) | 20 (28.6) | 50 (71.4) | |
No | 301 (81.1) | 114 (37.9) | 187 (62.1) | |
Hematopoietic stem cell transplantation | < 0.001 | |||
Yes | 104 (28) | 56 (54.4) | 47 (45.6) | |
No | 267 (72) | 78 (29.3) | 188 (70.7) | |
