Figure 2 | Scientific Reports

Figure 2

From: Pan-AMPK activator O304 prevents gene expression changes and remobilisation of histone marks in islets of diet-induced obese mice

Figure 2

O304 treatment improve islet gene expression signatures associated with β-cell stress and impaired insulin secretion. Dotplots of normalized read counts for β-cell stress genes in islets from RD controls (blue), HFD mice (red) and HFD-0304 mice (green) (n = 7 for all groups) Individual data points, mean ± SEM are indicated. The Wilcoxon rank sum test was applied. ns not significant, *p < 0.05, **p < 0.01, ***p < 0.001.

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