Table 2 Clinical and laboratory characteristics of patients according to their ICU-AW status at day 10 of their critical illness; p-values that indicate significant differences are printed in bold.

From: A novel ex vivo model for critical illness neuromyopathy using freshly resected human colon smooth muscle

Ā 

CINMāˆ’

CINM+

p-value

Patient no.

18

25

Ā 

mean age (years ± SD)

67.89 ± 14.7

66.6 ± 13.82

0.770

sex (% male)

0.72

0.64

0.570

mean APACHE II ± SD

25.11 ± 4.78

25.72 ± 6.13

0.727

SOFA ± SD day 3

10.28 ± 2.49

13.12 ± 2.86

0.002

SOFA ± SD day 10

4 ± 3.88

7.63 ± 4.13

0.006

% diabetes*

56

84

0.041

pH

7.42 ± 0.05

7.42 ± 0.07

0.854

K+ (mM)

4.31 ± 0.5

4.5 ± 0.45

0.199

Na+ (mM)

143.33 ± 3.68

144.16 ± 4.35

0.516

Ca2+ (mM)

1.16 ± 0.06

1.14 ± 0.07

0.596

Glucose (mM)

6.92 ± 1.3

7.64 ± 1.86

0.164

CRP (mg/l)

214.94 ± 143.32

231.42 ± 116.65

0.691

PCT (ng/ml)

5.02 ± 8.96

11.79 ± 21.13

0.209

Ā 

Healthy controls

Patients day 3

Ā 

CMAP ADM (mV)

13.3 ± 2.3

4.9 ± 2.2

< 0.0001

CMAP EDB (mV)

6.1 ± 2

1.6 ± 1.5

< 0.0001

SNAP radial nerve (µV)

41.7 ± 13.1

12.7 ± 6.6

< 0.0001

SNAP sural nerve (µV)

16.2 ± 4.3

11.8 ± 5.5

0.04

Ā 

Healthy controls

Patients day 10

Ā 

CMAP ADM (mV)

13.3 ± 2.3

5.5 ± 2.9

< 0.0001

CMAP EDB (mV)

6.1 ± 2

1.2 ± 1.3

< 0.0001

SNAP radial nerve (µV)

41.7 ± 13.1

14.2 ± 6.2

< 0.0001

SNAP sural nerve (µV)

16.2 ± 4.3

8.8 ± 5.1

< 0.001

  1. Demographic and clinical parameters except for the SOFA-score refer to the day of admission, laboratory parameters refer to day 3. For numerical data, p-values were calculated using t-tests for independent samples. For categorical data, χ2 tests were used.
  2. *Only patients without manifest diabetic polyneuropathy were included in this study.