Figure 3
From: Gut dysbiosis is associated with acceleration of lupus nephritis
Expansion of small intestinal Th17 cells and ILC3s in SFB colonized NZM2410 mice. (A) Gating strategy of small intestinal lamina propria Th17 (siTh17) cells and ILC3s (siILC3) in 30 week old mice. Gating is based on previous gating on the lymphocyte gate (top left panel), live and lineage negative markers (CD1a, CD3, CD4, CD14, CD11b, CD19, NK-1.1, F4/80). (B) RORγt+ siTh17 cells and siILC3s in mice colonized with SFB when compared to control mice (No SFB). (C) MHCII expression in siILC3s. Error bars represent mean ± SEM (B,C). Unpaired Student t test (B,C). *p < 0.05; **p < 0.005.
