Figure 6 | Scientific Reports

Figure 6

From: A selective CuII complex with 4-fluorophenoxyacetic acid hydrazide and phenanthroline displays DNA-cleaving and pro-apoptotic properties in cancer cells

Figure 6

Plasmid siSTRIKE degradation assay (A) Quantification of DNA percentage according to the electrophoresis pattern. Data are expressed as means ± standard deviation of three assays. Statistical analysis was performed with 2-way ANOVA and multiple comparison by Dunnett's test. *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001; ns not significant, compared to untreated control. (B) Representative agarose gel electrophoresis of plasmid DNA treated with complex 1, DMSO, H2O2 and Nhe I restriction enzyme. Circular, linear and supercoiled plasmid forms are indicated in the gel. Full-length gels are presented in Supplementary Figure S5.

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