Table 1 Participant characteristics on enrolment.

From: Abnormal whole-body energy metabolism in iron-deficient humans despite preserved skeletal muscle oxidative phosphorylation

Characteristic

ID Group (n = 13)

IR Group (n = 13)

P-value

Sex, M:F

1:12

1:12

 

Age, years

23 (21.5–38)

24 (22–25.5)

0.59

BMI, kg/m2

21.8 (20.8–24.1)

21.1 (20.7–24.1)

1.0

Resting Spo2, %

98.8 ± 0.9

98.5 ± 1.1

0.45

Systolic BP, mmHg

119 ± 11

119 ± 9

0.99

Diastolic BP, mmHg

73 ± 10

79 ± 8

0.08

FEV1, % predicted

106 ± 12

104 ± 9

0.75

Exercise, h/week

5.0 (2.0–7.5)

4.0 (1.0–8.5)

0.70

Plasma CRP, mg/L

0.4 (0.3–2.6)

0.5 (0.3–1.6)

0.96

Serum ferritin, μg/L

8.3 ± 3.1

58.0 ± 38.2

N/A

Serum TSat, %

10.6 ± 3.9

35.2 ± 7.6

N/A

Serum iron, μmol/L

8.4 ± 3.2

22.0 ± 3.6

< 0.001

Serum transferrin, g/L

3.6 ± 0.6

2.9 ± 0.5

0.003

Plasma sTfR, nmol/L

38.4 (32.7–50.9)

21.8 (18.4–25.0)

< 0.001

Plasma hepcidin, μg/L

2.0 (1.3–2.4)

13.9 (9.9–29.5)

< 0.001

Haemoglobin, g/dl

12.7 (11.5–13.3)

13.6 (13.5–14.0)

< 0.001

Haematocrit, %

39.7 ± 3.2

42.0 ± 1.7

0.028

Mean cell volume, fl

86.9 (83.0–91.3)

92.4 (89.9–94.1)

0.010

  1. For normally distributed data, comparisons are by t-test and values are means ± SD. For non-normally distributed data, comparisons are by Mann Whitney U test and values are medians (IQR). Statistically significant P-values appear in bold. ID, iron deficient; IR, iron replete; BMI, body mass index; Spo2, peripheral oxyhaemoglobin saturation; FEV1, forced expiratory volume in one second; CRP, C-reactive protein; TSat, transferrin saturation; sTfR, soluble transferrin receptor.
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