Table 2 Haematological and iron parameters over the course of the study.

From: Abnormal whole-body energy metabolism in iron-deficient humans despite preserved skeletal muscle oxidative phosphorylation

Iron status

Iron deficient (n = 13)

Iron replete (n = 13)

P-value for interactions (RM-ANOVA)

Intervention

Iron (n = 7)

Saline (n = 6)

Iron (n = 7)

Saline (n = 6)

Visit & intervention

Iron status, visit & intervention

Visit

1

2

1

2

1

2

1

2

Hb, g/dl

13.1 ± 1.1

13.0 ± 1.3

12.7 ± 0.6

12.5 ± 0.7

14.3 ± 0.7

13.7 ± 0.9

14.1 ± 0.4

13.9 ± 0.6

0.66

0.43

MCV, fl

84.4 ± 7.6

87.1 ± 6.8

86.0 ± 3.9

86.0 ± 4.3

91.9 ± 5.7

91.4 ± 2.6

90.9 ± 3.2

91.3 ± 2.3

0.47

0.09

Serum ferritin, μg/L

7.9 ± 3.5

561 ± 433

6.9 ± 2.4

10.6 ± 2.8

56.3 ± 35.5

840 ± 331

29.0 ± 14.3

38.7 ± 16.2

< 0.001

0.32

Serum TSat, %

12.3 ± 4.9

37.9 ± 11.2

13.7 ± 5.5

11.0 ± 2.8

29.0 ± 8.8

62.1 ± 20.1

23.0 ± 5.5

24.3 ± 12.5

< 0.001

0.73

Serum iron, μmol/L

9.3 ± 2.6

24.0 ± 9.1

11.1 ± 4.8

8.7 ± 2.0

17.8 ± 4.8

31.2 ± 10.4

16.2 ± 4.3

16.5 ± 8.2

< 0.001

0.54

Serum transferrin, g/L

3.61 ± 0.77

2.90 ± 0.48

3.65 ± 0.49

3.68 ± 0.44

2.83 ± 0.34

2.32 ± 0.26

3.17 ± 0.40

3.13 ± 0.39

< 0.001

0.27

Plasma sTfR, nmol/L

40.3 ± 12.0

33.4 ± 7.6

41.8 ± 13.1

40.9 ± 14.0

24.3 ± 3.5

20.7 ± 4.2

22.5 ± 2.5

21.7 ± 2.0

0.007

0.30

Serum Epo, mIU/ml

17.7 ± 9.2

13.6 ± 3.9

13.8 ± 4.7

21.3 ± 7.8

8.0 ± 2.8

7.6 ± 4.0

7.7 ± 2.4

7.2 ± 2.1

0.016

0.015

Plasma hepcidin, μg/L

2.1 ± 1.2

38.5 ± 28.9

1.5 ± 0.5

2.1 ± 1.0

17.2 ± 22.6

85.5 ± 54.6

7.3 ± 3.3

14.6 ± 14.7

< 0.001

0.30

  1. Values are means ± SD. Statistically significant P-values appear in bold. RM-ANOVA, repeated measures analysis of variance; MCV, mean cell volume; TSat, transferrin saturation; sTfR, soluble transferrin receptor; Epo, erythropoietin.
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