Figure 4 | Scientific Reports

Figure 4

From: Identifying gene expression profiles associated with neurogenesis and inflammation in the human subependymal zone from development through aging

Figure 4

Transcripts whose expression rose steadily over the course of aging. (A) The second major profile that we identified related to genes whose expression increased steadily over the course of aging. There were 629 genes associated with this profile. Ingenuity analysis revealed many immune-associated pathways associated with this profile (B), as well as many immune-associated upstream regulators potentially linked to it (C). (D,E) qPCR analysis confirmed the steady rise in the expression of IL13RA2 (D) and IL18 (E). Colours for significance (***) correspond to the colour of the age group used in the comparison. *p < 0.05, **p < 0.01, ***p < 0.001; Analysis of variance, post hoc tests using LSD.

Back to article page