Table 4 Driver genes predicted for each of the cancer types.

From: Novel ratio-metric features enable the identification of new driver genes across cancer types

Primary tissue

Genes

Breast cancer

TP53, CBFB, RUNX1, CDH1, GATA3, PTEN, TBX3

Central nervous system

TP53, HCN1

Endometrium

KRAS, PIK3R1, PTEN

Hematopoietic

TP53, B2M, CCND3, HLA-A

Kidney

PBRM1, VHL, TP53

Large intestine

TP53, FBXW7, FAM182A, SOX9, AHNAK2, TCF7L2, ENSG00000121031, FLT3LG, PMEPA1, ZFP36L2

Liver

TP53, ALB, KRTAP19-1, APOB, CD200, CRYGD, KRTAP24-1, OR6N2

  1. The genes reported showed consensus for > 4 CV models. Genes in bold did not find similar consensus in the pan-cancer predictions. New genes are underlined.