Figure 4 | Scientific Reports

Figure 4

From: High cell surface expression and peptide binding affinity of HLA-DQA1*05:03, a susceptible allele of neuromyelitis optica spectrum disorders (NMOSD)

Figure 4

The energetic stability of pMHC complex. (A) Procedure for modeling and calculation of EMPIRE score using ImmuneScape. This schema was created with BioRender.com. (B, C) Comparison of energetic pMHC complex stability between three HLA-DQA1 alleles binding. (B) EMPIRE score with each immunodominant AQP4 peptide. (C) Average EMPIRE score with all seven immunodominant AQP4 peptides.

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