Table 2 Laboratory records and inflammation markers of patients infected with Influenza A (H1N1) on admission.

White blood cell count × 10⁹/L (4–10)

5.9 (5.2, 6.5)

7.2 (5.5, 9.0)

10.3 (6.0, 16.1)^b

0.024

 < 4

0

2, 13.33%

2, 5.26%

0.044

4–10

30

11, 73.33%

17, 44.74%

…

 > 10

0

2, 13.33%

19, 50.00%

…

Lymphocyte count × 10⁹/L (1–3)

1.8 (1.4, 2.3)

0.9 (0.6, 1.6)

0.6 (0.5, 0.9)^b

0.042

 ≤ 0.5

0

3, 20.00%

16, 42.11%^a

 < 0.001

0.5- 1.0

0

7, 46.67%

15, 39.47%

…

 ≥ 1.0

30

5, 33.33%

7, 18.42%

…

Lymphocyte percentage (%) (20–40)

31.8 (24.7 36.4)

14.5 (8.6, 22.4)

7.2 (4.6, 12.4)^b

0.017

CD4 + T Lymphocytes (%) (30.1–44.4)

–

41.4 ± 8.2

36.4 ± 11.8

0.244

CD8 + T Lymphocytes (%) (20.7–29.4)

–

22.2 ± 5.3

23.2 ± 8.0

0.733

CD4/CD8 (1.02–1.94)

–

1.77 (1.40, 2.66)

1.71 (0.92, 2.41)

0.569

Platelet count, × 10⁹/L (100–300)

256.0 (143.5, 284.0)

233.5 (173.0, 291.0)

154.0 (105.0, 255.0)

0.508

D-dimer, μg/mL (0–0.5)

–

0.32 (0.22, 0.68)

3.75 (1.50, 13.27)^b

 < 0.001

Albumin, g/L (40–55)

44.8 ± 3.1

38.0 ± 4.8

27.6 ± 4.0^c

 < 0.001

ALT, U/L (9–35)

17.4 (13.2, 24.6)

18.5 (16.4, 39.9)

34.3 (20.5, 56.1)^b

 < 0.001

 ≤ 35

30

11

21

0.226

 > 35

0

4

17

…

AST, U/L (15–40)

21.1 (18.9, 26.8)

23.1 (17.8, 27.0)

47.8 (34.8, 82.5)^b

0.033

 ≤ 40

30

14

14^a

 < 0.001

 > 40

0

1

24

…

Creatinine, μmol/L (0–135)

45.9 (38.1, 56.2)

60.3 (43.6, 66.9)

59.8 (47.3, 91.3)

0.622

LDH, U/L (0–430.6)

194.6 (165.3, 223.6)

223.9 (193.9, 239.5)

635.7 (375.6, 864.4)^b

 < 0.001

CK, U/L (25–200)

67.3 (47.1, 97.6)

65.9 (45.1, 130.5)

86.3 (42.8, 272.3)

0.365

PCT, μg/L (0–0.5)

–

0.06 (0.04, 0.13)

0.68 (0.40, 4.80)^b

0.001

Inflammation markers

TNF-α (pg/ml)

3.7 (1.3, 5.6)

8.4 (6.7, 13.3)^d

13.3 (11.7, 23.2)^{b, d}

0.001

IL-6 (pg/ml)

1.9 (0.5, 5.9)

3.4 (2.6, 5.5)^d

71.2 (16.6, 182.0) b, d

 < 0.001

IL-10 (pg/ml)

5.9 (4.7, 6.5)

9.1 (6.6, 15.9)^d

22.4 (12.3, 52.6)^{b, d}

 < 0.001