Figure 2

Correlation matrix of all variables (both dependent and independent). As expected “Median age of the population”, “Population aged 65 or older”, and “Population aged 70 or older” have mutual correlation close to 1; also the genetic features are highly correlated with each other. The TDPMs at the three different dates are also highly correlated with each other, as expected. Notably, the “B+” predictor has the highest (and negative) linear correlation with the TDPM at all three dates. R package corrplot 0.90 was used to generate the figure.