Figure 1 | Scientific Reports

Figure 1

From: Expression of type I interferon-associated genes at antiretroviral therapy interruption predicts HIV virological rebound

Figure 1

GSEA and WGCNA module identification and enrichment. (A) The top ten enriched pathways (FDR < 0.25) for Week 48 PTC vs ER by GSEA. Ranking is by Normalised Enrichment Score (NES). (B) Heatmap plot of WGCNA gene modules on TI associated with ‘days to rebound’. Trait correlations and statistical significance (in parenthesis) are shown for each module. Modules are colour-coded based on direction and intensity of correlation. The ‘salmon’ module which was identified for further analysis is marked with a box and labelled as ‘Module 1’. The heatmap was made with WGCNA (package version 1.70.3). (C) Scatterplot of gene significance (GS) for trait of interest versus module membership (MM) for Module 1.

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