Table 2 Univariable Cox regression for individual hub genes.

From: Expression of type I interferon-associated genes at antiretroviral therapy interruption predicts HIV virological rebound

 

HR (95% CI for HR)

p value

ISG15

0.29 (0.11–0.81)

0.0091

IFI6

0.18 (0.037–0.86)

0.014

IFI44L

0.55 (0.27–1.1)

0.083

IFI44

0.23 (0.047–1.2)

0.045

IFIT1

0.37 (0.12–1.1)

0.054

OAS3

0.52 (0.22–1.3)

0.15

XAF1

0.3 (0.1–0.92)

0.027

TRIM25

0.074 (0.0068–0.8)

0.023

CMPK2

0.23 (0.037–1.5)

0.074

RSAD2

0.2 (0.041–0.99)

0.032

EIF2AK2

0.54 (0.12–2.4)

0.42

USP18

0.23 (0.062–0.84)

0.022

HERC6

0.16 (0.019–1.3)

0.057

  1. Hub genes identified by the WGCNA analysed contained within the ‘salmon’ Module 1. Genes in bold have p < 0.05 and were selected for the multivariable Cox/LASSO regression. HR hazard ratio, 95% CI 95% confidence intervals.