Table 2 Unadjusted and adjusted odds ratios for single nucleotide polymorphisms in subjects without incident delirium compared to those with incident delirium.

From: KIBRA, MTNR1B, and FKBP5 genotypes are associated with decreased odds of incident delirium in elderly post-surgical patients

Single nucleotide polymorphism

Unadjusted Odds Ratio (95% CI)

P-value

Adjusted Odds Ratio (95% CI)

P-value

FKBP5 SNP rs1360780 (CT/TT vs CC)

2.28 (0.94, 5.56)

0.07

2.51 (1.00, 7.34)

0.05

KIBRA SNP rs17070145 (CT/TT vs CC)

2.29 (0.94, 5.56)

0.07

2.80 (1.03, 7.54)

0.04

KLOTHO SNP rs9536314 (TT/GG vs TG)

0.63 (0.25, 1.64)

0.35

0.59 (0.21, 1.61)

0.30

MTNR1B SNP rs10830963 (CG/GG vs CC)

3.40 (1.25, 9.21)

0.02

4.14 (1.36, 12.59)

0.01

SIRT-1 SNP rs7896005 (GG vs GA/AA)

1.77 (0.78, 4.02)

0.16

1.72 (0.73, 4.05)

0.21

  1. CI confidence interval, FKBP5 FK506 binding protein 51, KIBRA kidney and brain expressed protein, MTNR1B Melatonin Receptor-1B, SIRT 1 sirtuin 1, SNP single nucleotide polymorphism.
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