Figure 1 | Scientific Reports

Figure 1

From: PRMT3 inhibitor SGC707 reduces triglyceride levels and induces pruritus in Western-type diet-fed LDL receptor knockout mice

Figure 1

(A) Absolute and body weight (BW) corrected liver weights, and liver relative mRNA expression levels of lipogenic genes (B) and triglyceride levels (C) in livers of Western-type diet-fed male LDL receptor knockout mice treated with the PRMT3 inhibitor SGC707 or the solvent control. Values in the graphs represent the means + SEM of 11 mice per group. *P < 0.05, **P < 0.01, ***P < 0.001 versus control. (D) Representative images of hematoxylin/eosin-stained liver sections showing marked steatosis, i.e. lipid droplets, only in tissue of the control group (magnification: 400×).

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