Figure 2 | Scientific Reports

Figure 2

From: PRMT3 inhibitor SGC707 reduces triglyceride levels and induces pruritus in Western-type diet-fed LDL receptor knockout mice

Figure 2

(A) The distribution of cholesterol and triglycerides over very-low-density lipoprotein (VLDL), low-density lipoprotein (LDL), and high-density lipoprotein (HDL) fractions and (B) plasma total lipid levels in Western-type diet-fed male LDL receptor knockout mice treated with the PRMT3 inhibitor SGC707 or the solvent control. Values in the graphs represent the means + SEM of 11 mice per group. *P < 0.05 versus control. (C) Representative images of Oil red O-stained aortic root sections with arrows indicating the minimal vascular lipid deposition (magnification: 50×).

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