Figure 6

Hepatic gene expression (A) and free cholesterol and cholesteryl ester (B) levels and plasma ALT levels (C) in Western-type diet-fed male LDL receptor knockout mice treated with the PRMT3 inhibitor SGC707 or the solvent control. Values in the graphs represent the means + SEM of 9–11 mice per group. *P < 0.05 versus control.