Table 1 Demographic and clinical characteristics of the study patients.

From: Development and validation of a prediction model to estimate risk of acute pulmonary embolism in deep vein thrombosis patients

Characteristic

n (%) or median (IQR)

DVT

DVT + APE

n = 687

n = 773

Sex

Male

330 (48)

373 (48)

Female

357 (52)

400 (52)

Age

59 (48, 68)

62 (51, 70)

Pre-existing disease or condition

Heart failure

21 (3.1)

19 (2.5)

Respiratory failure

1 (0.1)

31 (4.0)

Previous history of VTE

76 (11)

43 (5.6)

Autoimmune disease

17 (2.5)

26 (3.4)

Malignant tumor

77 (11)

59 (7.6)

Risk factors

Fracture of lower limb

65 (9.5)

96 (12)

Severe trauma

32 (4.7)

36 (4.7)

Spinal cord injury

5 (0.7)

15 (1.9)

Arthroscopic operation

23 (3.3)

14 (1.8)

Blood transfusion

25 (3.6)

32 (4.1)

Hormone replacement therapy

22 (3.2)

19 (2.5)

Infection

27 (3.9)

96 (12)

Paralytic stroke

36 (5.2)

46 (6.0)

Superficial venous thrombosis

19 (2.8)

6 (0.8)

Postpartum period

21 (3.1)

14 (1.8)

Stay in bed (> 3 days)/undergo surgery

181 (26)

210 (27)

Long time of sitting (> 6 h)

81 (12)

29 (3.8)

Undergo hysteroscopy/Laparoscopy surgery

29 (4.2)

31 (4.0)

Laricose vein of lower limb

46 (6.7)

43 (5.6)

Smoke

192 (28)

195 (25)

Symptoms

Dyspnea

28 (4.1)

302 (39)

Hemoptysis

3 (0.4)

33 (4.3)

Chest pain

13 (1.9)

90 (12)

Swelling and pain in the lower limbs

657 (96)

593 (77)

Fever

32 (4.7)

52 (6.7)

Syncope

8 (1.2)

99 (13)

Cough

33 (4.8)

74 (9.6)

Palpitation

5 (0.7)

31 (4.0)

Delirium/disturbance of consciousness

1 (0.1)

5 (0.6)

Signs

Skin cold clammy

7 (1.0)

27 (3.5)

Cyanosis of the lips

1 (0.1)

19 (2.5)

Tachycardia

36 (5.2)

109 (14)

Diminished respiration

1 (0.1)

43 (5.6)

Pulmonary rales

7 (1.0)

78 (10)

Accentuation/splitting of P2

100 (15)

178 (23)

Distention of jugular vein/hepatojugular reflex

2 (0.3)

8 (1.0)

ECG

Heart rate

78 (69, 89)

82 (72, 94)

SIQIIITIII

21 (3.1)

137 (18)

Nodal tachycardia

54 (7.9)

103 (13)

Right ventricular hypertrophy

0 (0)

13 (1.7)

Right axis deviation

4 (0.6)

19 (2.5)

Left axis deviation

55 (8.0)

176 (23)

S1S2S3

2 (0.3)

41 (5.3)

Low voltage

17 (2.5)

35 (4.5)

Clockwise rotation of cardiac electric axis

1 (0.1)

9 (1.2)

ST-segment elevation

10 (1.5)

14 (1.8)

ST-segment depression

33 (4.8)

91 (12)

T wave inversion(V1–V3/V4)

34 (4.9)

175 (23)

ST-segment depression(II/III/aVF)

14 (2.0)

71 (9.2)

Q/q wave(II/aVF)

17 (2.5)

74 (9.6)

T wave inversion(II/aVF)

6 (0.9)

56 (7.2)

Right bundle branch block

25 (3.6)

50 (6.5)

  1. ECG electrocardiogram, APE acute pulmonary embolism, DVT deep vein thrombosis, VTE venous thromboembolism, P2 pulmonary valve second heart sound.